Against the backdrop of the global ban on antibiotics, the poultry industry faces the challenge of maintaining bird health and performance while reducing antibiotic use. yeast hydrolysate, a yeast-derived protein product which rich in nucleotides and functional proteins, can improve feed intake, body weight, and gut health in layer chicks during the brooding period. GroPro is a nucleotide and protein-rich product produced by Angel Yeast Co., Ltd. It is a yeast-derived protein ingredient that provides digestible protein and functional nucleotides specially for young animals, supporting them through the critical early growth stages. GroPro supplies exogenous nucleotides to young animals, thereby saving the time and energy required for nucleotide synthesis and promoting faster growth. The protein in GroPro exists as main in form of free amino acids and small peptides, which further assists protein synthesis and digestion.
According to recent research findings:
1. Effects of GroPro Supplementation on the Performance of Layer Chicks
Compared to the control group (T0), the T3 group (diet supplemented with 10 kg/ton GroPro) significantly increased the feed intake of layer chicks (p<0.01). Furthermore, the final body weight and daily weight gain increased by 7.29 g/bird and 5.97 g/bird, respectively.
Table 1. Effect of different treatment on the layer performances
Note: NS: non - significant, **:a-c in the different row showed significantly different (p<0.01) on the treatment.
2. Effects of GroPro Supplementation on the Intestinal Physical Barrier of Layer Chicks
Compared to the control group, the number of small intestinal villi per chick showed an increasing trend in the T1 (diet supplemented with 2 kg/ton GroPro), T2 (diet supplemented with 5 kg/ton GroPro), and T3 (diet supplemented with 10 kg/ton GroPro) groups. Specifically, the villus count in the T3 group reached 20.5, which was higher than the 18.83 observed in the control group (T0). Furthermore, villus tip width, villus base width, crypt depth, and villus area in the layer chicks increased significantly. These results indicate that GroPro supplementation can significantly improve the intestinal physical barrier function of layer chicks.
Table 2.Effect of different treatment on the intestinal characteristic of laying hens
Note: NS: non-significant, *: a-c in the different row showed significantly different (p < 0.05) on the treatment; **: a-c in the different row showed significantly different (p < 0.01) on the treatment.
3. Effects of GroPro Supplementation on the Intestinal Microbial Barrier of Layer Chicks
The control group and the 10 kg/ton supplementation group shared 19 families and 35 genera. However, the treatment group supplemented with yeast contained 6 unique families and 10 unique genera, while no unique taxa were identified in the control group. This indicates that yeast supplementation expanded the taxonomic range of the microbiota at both the family and genus levels.Furthermore, GroPro supplementation successfully restored the diversity and structural balance among Lactobacillus species. These findings demonstrate that yeast supplementation at 10 kg/ton exerted a positive remodeling effect on the gut microbiota by enhancing diversity, enriching beneficial taxa, and promoting the formation of a functional microbial network conducive to growth and health.
Fig 1. Abundance of gut microbiota identified from broilers fed with yeast extract. A) Venn Diagram describing about the number of taxa observed in each group at family and genus level, B) abundance profile of microbes at phylum level, C) abundance value of top 10 taxa at family level, and D) abundance profile of top 10 taxa at genus level.
4. Conclusion
This study demonstrates that GroPro, a yeast-derived protein ingredient rich in nucleotides, proteins, and functional oligosaccharides, selectively improves intestinal morphology, immune response, and microbial ecology in layer chicks. Among the tested treatment groups, the 10 kg/ton (T3) GroPro supplementation regimen yielded optimal performance.
About Angel Animal Nutrition
Angel Animal Nutrition focuses on providing professional yeast solutions for animal nutrition, caring for animal health, reducing antibiotic use, and promoting the sustainable development of the livestock industry. Together with our partners, we are always in action, working hand in hand to create a better future.
About Angel
Angel Yeast Company is a high-tech listed company specializing in yeast and biotech. Product business covers Yeast and Baking, Yeast Extract-Savoury, Nutrition & Health and Biotechnology fields. It is one of the world's leading companies in the yeast industry. Angel has 12 holding subsidiaries and provides products and services for more than 150 countries and regions.
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