Comparison of Yeast Glucan and other Glucans
Glucan can be widely found in nature, including plants, fungi, bacteria, etc;
The differences of molecular structure lead to significant differences in their efficacy.
β-glucan structure-activity mechanism
The content of β-1, 3 - glucan is a key factor in its role. The length and number of branched chain is the key to the specific binding of the immune cells.
Bacterial Source: Single β-1, 3 - glucan cannot effectively bind to receptors on immune cells.
Grain Source: β-1, 4 - glucan cannot enhance the immune activity, and without β-1, 6 branch.
Mushroom Source:The degree of branching is high(too many branches), the branch is short.
Yeast Source: Suitable length of branched chain and single β-1, 3- glucan backbone could effect in the enhancing immune activity as best.
The difference between yeast glucan and oat glucan
1. The basic structure of Oat glucan is a linear polysaccharide which is connected by D-glucose with β 1-4, β 1-3 glycosidic bond.The rough ratio of these two glycosidic bond is about 7:3. and yeast glucan is connected by D-glucose, with β-1-3 glycosidic bond as the main chain, and β-1-6 glycosidic bond as a branched chain, as the content of β-1, 3 - glucan is the key factor of effect, so oat glucan immune reactivity is significantly lower than the yeast glucan.
2. Studies have shown that the yeast glucan and oat glucan can lower LDL, but the yeast glucan can significantly increase high-density lipoprotein (HDL), but oat glucan have no such function.
3. The research of Yeast glucan is broader and more in-depth, that it have some effects on the immune system, radiation damage and tumor recession. Scientists have found yeast beta-glucan-specific receptors on the cells which enhance immunity and anti-tumor immunity.
4. Find more studies of yeast glucan on: http://www.betaglucan.org/